Ethanol, Acetaldehyde And
نویسنده
چکیده
Regulatory factors and pathophysiological consequences of microbial ethanol oxidation and acetaldehyde production in the digestive tract
منابع مشابه
Evaluation of Flavor and Aroma Compounds Present in Kefir
ABSTRACT: Kefir is fermented milk that has a unique flavor because of acetaldehyde, diacetyl, acetoin and ethanol. The aim of this study was to evaluate flavor and aroma compounds present in kefir. Two types of starter (Christian Hansen and Sacco) and three levels of temperatures (30, 33 and 35oC) were used for the preparation of kefir samples. The samples were analyzed for acetaldehyde, diacet...
متن کاملHigh intracolonic acetaldehyde values produced by a bacteriocolonic pathway for ethanol oxidation in piglets.
BACKGROUND Human colonic contents and many colonic microbes produce considerable amounts of acetaldehyde from ethanol in vitro. AIMS To examine in piglets if acetaldehyde is produced in the colon also in vivo, and if so, what is the fate of intracolonically formed acetaldehyde. ANIMALS Seventeen native, non-fasted female piglets (20-25 kg) were used. METHODS Six piglets received either 1....
متن کاملCalcium Channels and Oxidative Stress Mediate a Synergistic Disruption of Tight Junctions by Ethanol and Acetaldehyde in Caco-2 Cell Monolayers
Ethanol is metabolized into acetaldehyde in most tissues. In this study, we investigated the synergistic effect of ethanol and acetaldehyde on the tight junction integrity in Caco-2 cell monolayers. Expression of alcohol dehydrogenase sensitized Caco-2 cells to ethanol-induced tight junction disruption and barrier dysfunction, whereas aldehyde dehydrogenase attenuated acetaldehyde-induced tight...
متن کاملUtilization and metabolic effects of acetaldehyde and ethanol in the perfused rat liver.
1. Removal of acetaldehyde and ethanol has been studied in perfused rat livers. 2. The maximum rate of ethanol oxidation was 2mumol/min per g of liver, which was less than the calculated capacity of the ethanol-oxidizing system. The lactate/pyruvate ratio of the medium increased with the rate of ethanol removal. At low ethanol concentrations most of the acetaldehyde formed was oxidized further,...
متن کاملAcetaldehyde concentrations in alveolar air following a standard dose of ethanol in man.
A method for serial gas chromatographic determinations of acetaldehyde, acetone, and ethanol in alveolar air is described. The concentration of alcohol in alveolar air increased rapidly and then declined linearly following ingestion of ethanol, 0.5 ml/lb body weight, drunk as a 10% solution in 30 min. Acetaldehyde in alveolar air a t first increased rapidly to a maximum concentration, then decr...
متن کاملAn accurate, automated, simultaneous gas chromatographic headspace measurement of whole blood ethanol and acetaldehyde for human in vivo studies.
Simultaneous assessment of ethanol and acetaldehyde concentrations is necessary to address hypotheses in alcohol research. Accurate measurement of in vivo acetaldehyde following ethanol exposure is problematic because acetaldehyde is present in blank blood, is volatile, and is formed enzymatically and nonenzymatically in blood containing ethanol. Because acetaldehyde is carried in red blood cel...
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تاریخ انتشار 2000